Cape Girardeau, MO jobs, layoffs and employers

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Show me jobs near meJobs in Cape Girardeau
- Trauma Sales Representative - Southeast MO (Cape Girardeau, MO)Stryker Sales
- OnSite Specialist - Cape Girardeau, MOStryker Sales
- Pediatric Sales Specialist - Cape Girardeau, MOAbbott Laboratories
- MGR - NURSINGUniversal Health Services
- Attorney - Cape Girardeau/JacksonState of Missouri
- Junior Software Engineer: AI-Driven Full-Stack GrowthVizient
- Director, Institute for Cybersecurity - College of Business and ComputingSoutheast Missouri State University
- Chief Nursing OfficerCredenza Health
- General ManagerGecko Hospitality
- Data & Performance Analyst for Regional Workforce ProgramsCommunity-Partnership-of-Southeast-Missouri
Employers hiring most in Cape Girardeau
- Stryker Sales2 open roles
- Vizient2 open roles
- Abbott Laboratories1 open role
- Aegis Sciences1 open role
- Buzzi Unicem USA1 open role
- Cintas1 open role
- Community-Partnership-of-Southeast-Missouri1 open role
- Credenza Health1 open role
- EquipmentShare1 open role
- Gecko Hospitality1 open role
Cape Girardeau layoffs
No layoff notices naming Cape Girardeau in the last 12 months are on file. The WARN Act covers employers with 100 or more workers, so smaller layoffs are not in it.
Colleges in Cape Girardeau
| College | Type | Students |
|---|---|---|
| Southeast Missouri State University | Public 4-year | 5,000–9,999 |
| Southeast Missouri Hospital College of Nursing and Health Sciences | Private non-profit 4-year | Under 1,000 |
Cape Girardeau County outlook: Steady
Built from public Bureau of Labor Statistics and Census figures. It describes the area, not any one employer in it.
- Private-sector jobs up 1.3% from 2022 to 2025
- Population up 2.7% from 2020 to 2025
- Unemployment 2.9%, down 0.2 points from a year ago
- Sectors adding the most jobs: health care (+907 jobs)
- Sectors losing the most jobs: professional & technical (−459 jobs)
Learn and get funded in Cape Girardeau
- Which AI skills each kind of job asks for, with the pay premium.
- Your local workforce board and American Job Centers: training vouchers and re-employment help.
- Grants and funding for job seekers, ranked for your state and situation.
- Unemployment benefits by state, if you are between jobs.
Workforce development and job centers
The public workforce board and American Job Centers serving Cape Girardeau. They offer free help with job search, training and filing for benefits.
Laid off in Missouri? How to file for unemployment in Missouri (steps, weekly amount and the appeal deadline).
- Workforce Development Board of Southeast Missouri
Bollinger, Cape Girardeau, Madison, Mississippi, New Madrid, Pemiscot, Perry, Scott, St. Francois, Ste. Genevieve, Stoddard
Missouri Job Center - Cape Girardeau
Cape Girardeau · Affiliate · 573-381-2464
Mon, Tues, Wed, Thurs, 8:00 a.m. to 5:00 p.m. Friday 8:30 am-4:00 pm
Cape Girardeau County economy
2.9%
unemployment, Sep 2026
3.1% the month before
43,141
in the labor force
Source: BLS Local Area Unemployment Statistics
82,180
people in Cape Girardeau County
Source: U.S. Census Bureau
$68,912
median household income
Source: Census ACS
39%
of workers in white-collar occupations
Management, business, financial and professional; Census ACS
Laid off or looking for work in Cape Girardeau?
See what to do first and the jobs open near you.
See your options after a layoffSources: Layoff notices from Missouri’s published record; job counts from our live job board, taken from employers’ own career sites; IPEDS for colleges; CareerOneStop for workforce boards and job centers; Census Bureau and BLS for county figures. Missouri unemployment benefits and severance rules.
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