Cape Girardeau County, MO jobs, unemployment and layoffs

Cape Girardeau County’s unemployment rate is 2.9%. No layoff notices here in the last 12 months. 21 open professional jobs are in its cities.

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Cape Girardeau County economy

  • 2.9%

    unemployment, Sep 2026

    3.1% the month before

  • 43,141

    in the labor force

    Source: BLS Local Area Unemployment Statistics

  • 82,180

    people in Cape Girardeau County

    Source: U.S. Census Bureau

  • $68,912

    median household income

    Source: Census ACS

  • 39%

    of workers in white-collar occupations

    Management, business, financial and professional; Census ACS

Cape Girardeau County outlook: Steady

Built from public Bureau of Labor Statistics and Census figures. It describes the area, not any one employer in it.

  • Private-sector jobs up 1.3% from 2022 to 2025
  • Population up 2.7% from 2020 to 2025
  • Unemployment 2.9%, down 0.2 points from a year ago
  • Sectors adding the most jobs: health care (+907 jobs)
  • Sectors losing the most jobs: professional & technical (−459 jobs)

Learn and get funded in Cape Girardeau County

Cape Girardeau County layoffs

No layoff notices naming Cape Girardeau County in the last 12 months are on file. The WARN Act covers employers with 100 or more workers, so smaller layoffs are not in it.

All layoff notices in the state

Employers hiring most in Cape Girardeau County

Employers with the most open professional roles in this county’s cities. The county is taken from each job’s city, so roles with no city are not counted.

  1. Vizient2 open roles
  2. Aegis Sciences1 open role
  3. Alzheimer's Association1 open role
  4. Buzzi Unicem USA1 open role
  5. Cintas1 open role
  6. Community Counseling Center (CCC)1 open role
  7. Community-Partnership-of-Southeast-Missouri1 open role
  8. Credenza Health1 open role
  9. EquipmentShare1 open role
  10. EquipmentShare.com1 open role

Colleges in Cape Girardeau County

Colleges in Cape Girardeau County
CollegeCityTypeStudents
Southeast Missouri State UniversityCape GirardeauPublic 4-year5,000–9,999
Southeast Missouri Hospital College of Nursing and Health SciencesCape GirardeauPrivate non-profit 4-yearUnder 1,000

Workforce development and job centers

The public workforce board and American Job Centers serving Cape Girardeau County. They offer free help with job search, training and filing for benefits.

Laid off in Missouri? How to file for unemployment in Missouri (steps, weekly amount and the appeal deadline).

  • Missouri Job Center - Cape Girardeau

    Cape Girardeau · Affiliate · 573-381-2464

    Mon, Tues, Wed, Thurs, 8:00 a.m. to 5:00 p.m. Friday 8:30 am-4:00 pm

Cities in Cape Girardeau County

Other Missouri counties

All of Missouri

Laid off or looking for work in Cape Girardeau County?

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See your options after a layoff

Sources: Census Bureau and BLS (county unemployment is not seasonally adjusted); layoff notices from Missouri’s published record; job counts from our live job board; IPEDS for colleges; CareerOneStop for workforce boards and job centers. Missouri unemployment benefits and severance rules.

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