NextChapter

Principal Scientist jobs: 54 open roles

Open principal scientist jobs taken from employers’ own career sites and checked to still be open.

The market for principal scientist work

Every figure names its source. Skills and AI-skill shares describe the whole Research function this title sits in.

Verified open principal scientist jobs
54

Source: NextChapter, checked against employer career sites, last 7 days.

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Research openings that ask for AI skills
9%

Source: NextChapter verified openings.

Research openings that are remote
4%

Source: NextChapter verified openings.

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Skills most often named in openings

  1. 1. python9%
  2. 2. excel8%
  3. 3. project management7%
  4. 4. machine learning7%
  5. 5. powerpoint4%
  6. 6. regulatory compliance3%
  7. 7. matlab3%
  8. 8. agile2%

AI skills worth building for this work

  1. 1. AI tools in daily work
  2. 2. Gen-AI assistants (ChatGPT, Copilot, Claude)
  3. 3. Prompt design
  4. 4. AI coding assistants
  5. 5. AI workflow automation
  6. 6. Automation platforms (Zapier, n8n, Power Automate)

More on Research roles

Where principal scientist experience can go next

Career moves the skills carry over to, closest fit first. Time is how long a move usually takes.

  • Data science and machine learning

    Close fit · A few months

    Data science is the most common move out of the lab: same scientific method, applied to business data.

    Carries over: Statistics, Experiment design, Programming for analysis

  • Compliance and risk

    Close fit · A few months

    Regulatory affairs and quality roles at pharma, biotech and manufacturing companies want scientists.

    Carries over: Regulatory knowledge, Documentation, Quality systems

  • Clinical operations and care coordination

    Adjacent · A few months

    Clinical research and study management roles build on lab and research experience.

    Carries over: Research protocols, Data integrity, Study management

  • Solutions consulting and sales engineering

    Adjacent · A few months

    Application scientist and technical sales roles pay more for scientists who like people.

    Carries over: Deep technical knowledge, Explaining science simply, Solving customer problems

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Open principal scientist jobs

Verified against the employer’s own career site within the last week.

Showing the newest 15 of about 54 verified open jobs here. Search all jobs

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Where principal scientist jobs are

Between jobs? Unemployment benefits and severance rules in these states, or in every state.

Principal Scientist jobs by city and state

Employers hiring principal scientists

  • MSD 3
  • Calico 3
  • Praxis Precision Medicines 3
  • Colgate Palmolive 3
  • Boehringer Ingelheim 3
  • GSK 2
  • C4 Therapeutics 2
  • Scholar Rock Holding 2
  • Estee Lauder Companies 2
  • Brio 2

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