Principal Scientist jobs in California: 20 open roles
20 open principal scientist jobs in California, taken from employers’ own career sites and checked to still be open.
Open principal scientist jobs in California
Verified against the employer’s own career site within the last week.
- Principal Scientist, External Quality Analytical Oversight
Gilead Sciences · United States - California - Foster City
Nov 11, 2026
- Principal Scientist - Medicinal Chemistry
Amgen · San Francisco, CA
Nov 10, 2026
- Principal Scientist | REMOTE
Sonova USA · Valencia (CA), United States
Nov 7, 2026
- Principal Scientist, GI/Liver Biomarkers & Translational Research
Gilead Sciences · United States - California - Foster City
Nov 7, 2026
- Principal Scientist, Biotherapeutic Formulations
Halozyme Therapeutics · San Diego
Nov 5, 2026
- Principal Scientist, Translational Immunology & Antibody Discovery Innovation
Merck Patient Assistance Program · USA - California - South San Francisco (Grand Ave)
Nov 3, 2026
- Principal Scientist, Peptide Chemistry
Calico · South San Francisco, CA
Oct 22, 2026
- Principal Scientist
Cytokinetics · South San Francisco, California; United States of America
Oct 15, 2026
- Principal Scientist, Target Discovery & Portfolio Strategy
Xaira Therapeutics · South San Francisco, CA, USA
$164k–$205k · Oct 14, 2026
- Principal Scientist - Data Pipeline Engineer
Adobe · San Jose, California, United States of America
Oct 9, 2026
- Principal Scientist, Medicinal Chemistry
Iambic Therapeutics · San Diego HQ
$152k–$190k · Oct 5, 2026
- Principal Scientist, Oncology R&D
Hologic · San Diego, CA, United States
Sep 25, 2026
- Principal Scientist, DMPK
Calico · South San Francisco, CA
Sep 18, 2026
- Principal Scientist, Biology
Gilead Sciences · United States - California - Foster City
Sep 16, 2026
- Principal Scientist, Diagnostics (CDx), Associate Director
Gilead Sciences · United States - California - Foster City
Sep 2, 2026
Showing the newest 15 of about 20 verified open jobs here. Search all jobs
Search all principal scientist jobs in California · All principal scientist jobs
Employers hiring principal scientists in California
- Gilead Sciences 4
- Calico 3
- Adobe 1
- Amgen 1
- Cartography Biosciences 1
- Cytokinetics 1
- Halozyme Therapeutics 1
- Hologic 1
Other jobs in California
Local job market in California
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