St. Louis, MO jobs, layoffs and employers

858 open professional jobs in St. Louis. St. Louis is in St. Louis city.

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Jobs in St. Louis

Search all jobs in St. Louis

Employers hiring most in St. Louis

  1. Esri27 open roles
  2. Ameren15 open roles
  3. Hubbell13 open roles
  4. Sensient Technologies12 open roles
  5. Cannon Design10 open roles
  6. BDO USA9 open roles
  7. STERIS9 open roles
  8. Chenega Base & Logistics Services8 open roles
  9. Consigli Construction8 open roles
  10. Washington University in St. Louis8 open roles

Largest employers headquartered in St. Louis

Employee counts with a year are published figures (Wikidata). Other sizes are estimates from our company directory, not payroll counts.

St. Louis layoffs

No layoff notices naming St. Louis in the last 12 months are on file. The WARN Act covers employers with 100 or more workers, so smaller layoffs are not in it.

All layoff notices in the state

Colleges in St. Louis

Colleges in St. Louis
CollegeTypeStudents
Saint Louis UniversityPrivate non-profit 4-year10,000–19,999
University of Missouri-St LouisPublic 4-year10,000–19,999
Washington University in St LouisPrivate non-profit 4-year10,000–19,999
Maryville University of Saint LouisPrivate non-profit 4-year5,000–9,999
Missouri Baptist UniversityPrivate non-profit 4-year5,000–9,999
Webster UniversityPrivate non-profit 4-year5,000–9,999
Harris-Stowe State UniversityPublic 4-year1,000–4,999
Aquinas Institute of TheologyPrivate non-profit 4-yearUnder 1,000
Barnes-Jewish College Goldfarb School of NursingPrivate non-profit 4-yearUnder 1,000
Concordia SeminaryPrivate non-profit 4-yearUnder 1,000
Covenant Theological SeminaryPrivate non-profit 4-yearUnder 1,000
Fontbonne UniversityPrivate non-profit 4-yearUnder 1,000
Kenrick Glennon SeminaryPrivate non-profit 4-yearUnder 1,000
University of Health Sciences and Pharmacy in St. LouisPrivate non-profit 4-yearUnder 1,000

Job fairs and business events in St. Louis

Hiring events, career workshops and business events in St. Louis.

Conferences in St. Louis

Industry conferences and trade shows held in St. Louis. 7 with dates announced.

  • GEO Learning Conference

    May 26 to May 27, 2027 · St. Louis, MO

    Ticket $1,250 to $2,250. GEO members $1,250 priority/early, $1,500 regular, $2,250 late; Philanthropy Missouri members…

  • APTA Rail Conference

    Jun 6 to Jun 9, 2027 · St. Louis, MO

    Paid ticket. Pricing not found; APTA page also carries a stale 2026 Baltimore line.

  • NELA Annual Convention

    Jun 23 to Jun 26, 2027 · St. Louis, MO

    Ticket $725 to $915. 2026 early-bird member range; 2027 rates not posted; law students about $375-$400.

    Open call for speakers

  • FMI Fresh Forward

    Aug 2 to Aug 4, 2027 · St. Louis, MO

    Paid ticket. Pricing not seen.

  • NAWDP Business Services Academy

    Aug 9 to Aug 11, 2027 · St. Louis, MO

    Paid ticket, price not listed

  • The Missouri Bar Annual Meeting

    Sep 15 to Sep 17, 2027 · St. Louis, MO

    Paid ticket. Fees not on the page read. 2026 meeting is Sept 16-18 Kansas City; next is 2027.

  • NALS National Legal Education Conference

    Sep 27 to Sep 29, 2027 · St. Louis, MO

    Paid ticket. 2024 rates were $420-$630; 2027 not posted.

  • NLADA Annual Conference

    Usually November (next dates not announced) · St. Louis, MO

    Ticket $650 to $995. Early bird $650 member/$850 nonmember; regular $800/$995; late fee $75.

  • Community Banking Research Conference

    Usually October (next dates not announced) · St. Louis, MO

    By invitation only

All conferences

Where St. Louis ranks

Where St. Louis placed in our monthly rankings, month by month. Each month stays online at its own address.

St. Louis city outlook: Steady

Built from public Bureau of Labor Statistics and Census figures. It describes the area, not any one employer in it.

  • Private-sector jobs down 0.5% from 2022 to 2025
  • Population down 7.4% from 2020 to 2025
  • Unemployment 4.0%, down 0.2 points from a year ago
  • Sectors adding the most jobs: health care (+4,659 jobs), private education (+583 jobs)
  • Sectors losing the most jobs: finance & insurance (−1,824 jobs), admin & staffing (−1,339 jobs)

Local job-market news

Recent headlines about layoffs, AI and jobs in St. Louis. Each link goes to the publisher.

Learn and get funded in St. Louis

Workforce development and job centers

The public workforce board and American Job Centers serving St. Louis. They offer free help with job search, training and filing for benefits.

Laid off in Missouri? How to file for unemployment in Missouri (steps, weekly amount and the appeal deadline).

  • SLATE Missouri Job Center

    St. Louis · Comprehensive · 314-589-8000

    Mon, Tues, Thurs, Fri 8am-5pm Wed 9am-5pm

St. Louis city economy

  • 4.0%

    unemployment, Sep 2026

    4.2% the month before

  • 156,613

    in the labor force

    Source: BLS Local Area Unemployment Statistics

  • 293,109

    people in St. Louis city

    Source: U.S. Census Bureau

  • $55,279

    median household income

    Source: Census ACS

  • 48%

    of workers in white-collar occupations

    Management, business, financial and professional; Census ACS

All of Missouri

Laid off or looking for work in St. Louis?

See what to do first and the jobs open near you.

See your options after a layoff

Sources: Layoff notices from Missouri’s published record; job counts from our live job board, taken from employers’ own career sites; IPEDS for colleges; CareerOneStop for workforce boards and job centers; Census Bureau and BLS for county figures. Missouri unemployment benefits and severance rules.

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