Cambridge, MA jobs, layoffs and employers

823 open professional jobs in Cambridge. Employers filed 1 layoff notices here in the last 12 months. Cambridge is in Middlesex County.

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Jobs in Cambridge

Search all jobs in Cambridge

Employers hiring most in Cambridge

  1. Alnylam Pharmaceuticals61 open roles
  2. Lila Sciences54 open roles
  3. Takeda Development Center Americas48 open roles
  4. Blitzy25 open roles
  5. Massachusetts Institute of Technology (MIT)25 open roles
  6. Beam Therapeutics22 open roles
  7. Scholar Rock Holding22 open roles
  8. Takeda18 open roles
  9. Biogen17 open roles
  10. Harvard University17 open roles

Largest employers headquartered in Cambridge

Employee counts with a year are published figures (Wikidata). Other sizes are estimates from our company directory, not payroll counts.

Cambridge layoffs

  • 1

    Layoff notices, last 12 months

  • 229

    workers named

    A floor: states may leave out counts

  • 1

    employer

Layoff notices filed in Cambridge, newest first
Notice dateEmployerCity or countyWorkersTypeSource
Blueprint Medicines CorporationCambridge229—State record

All layoff notices in the state

Colleges in Cambridge

Colleges in Cambridge
CollegeTypeStudents
Harvard UniversityPrivate non-profit 4-year20,000+
Massachusetts Institute of TechnologyPrivate non-profit 4-year10,000–19,999
Hult International Business SchoolPrivate non-profit 4-year1,000–4,999
Lesley UniversityPrivate non-profit 4-year1,000–4,999
Longy School of Music of Bard CollegePrivate non-profit 4-yearUnder 1,000

Conferences in Cambridge

Industry conferences and trade shows held in Cambridge. 4 with dates announced.

  • SCALE Expo

    Jan 21, 2027 · Cambridge, MA

    Free

  • MIT Sloan Healthcare and BioInnovations Conference

    Feb 25 to Feb 26, 2027 · Cambridge, MA

    Paid ticket, price not listed

  • Crossroads

    Apr 7, 2027 · Cambridge, MA

    Paid ticket, price not listed

  • MIT Sloan CIO Symposium

    May 18, 2027 · Cambridge, MA

    Paid ticket. Price not seen.

  • dmi:Design Leadership Conference

    Usually September (next dates not announced) · Cambridge, MA

    Ticket $1,100 to $1,300. 2026 fees per dmi.org: members $1,100, non-members $1,300; 2027 not announced.

  • MIT CDOIQ Symposium

    Usually July (next dates not announced) · Cambridge, MA

    Ticket $950 to $1,950. 2027 pricing not published; prior editions listed roughly $950 to $1,950.

  • Leading Tribal Nations Executive Education Program

    Usually December (next dates not announced) · Cambridge, MA

    Apply to attend. $3,500 per participant including lodging and meals; page gives conflicting Dec 6-11 and Dec 7-12 dates

  • MIT ETA Summit

    Usually February (next dates not announced) · Cambridge, MA

    Paid ticket. 2026 edition (Feb 27-28) sold out/closed; 2027 not announced.

All conferences

Where Cambridge ranks

Where Cambridge placed in our monthly rankings, month by month. Each month stays online at its own address.

Middlesex County outlook: Steady

Built from public Bureau of Labor Statistics and Census figures. It describes the area, not any one employer in it.

  • Private-sector jobs down 2.8% from 2022 to 2025
  • Population up 2.8% from 2020 to 2025
  • Unemployment 3.8%, down 0.3 points from a year ago
  • Sectors adding the most jobs: health care (+8,939 jobs), management of companies (+5,973 jobs)
  • Sectors losing the most jobs: professional & technical (−18,366 jobs), admin & staffing (−7,990 jobs)

Local job-market news

Recent headlines about layoffs, AI and jobs in Cambridge. Each link goes to the publisher.

Learn and get funded in Cambridge

Workforce development and job centers

The public workforce board and American Job Centers serving Cambridge. They offer free help with job search, training and filing for benefits.

Laid off in Massachusetts? How to file for unemployment in Massachusetts (steps, weekly amount and the appeal deadline).

  • MassHire Greater Lowell Workforce Board

    Towns: Billerica, Chelmsford, Dracut, Dunstable, Lowell, Tewksbury, Tyngsborough, Westford

  • MassHire North Central Workforce Board

    Towns: Ashburnham, Ashby, Ayer, Barre, Berlin, Bolton, Clinton, Fitchburg, Gardner, Groton, Harvard, Hubbardston, Lancaster, Leominster, Lunenburg, Pepperell, Princeton, Shirley, Sterling, Templeton, Townsend, Westminster, Winchendon

  • Metro North Regional Employment Board

    Towns: Arlington, Belmont, Burlington, Cambridge, Chelsea, Everett, Malden, Medford, Melrose, North Reading, Reading, Revere, Somerville, Stoneham, Wakefield, Watertown, Wilmington, Winchester, Winthrop, Woburn

  • Metro South/West Workforce Board, Inc.

    Towns: Acton, Ashland, Bedford, Bellingham, Boxborough, Brookline, Canton, Carlisle, Concord, Dedham, Dover, Foxborough, Framingham, Franklin, Holliston, Hopkinton, Hudson, Lexington, Lincoln, Littleton, Marlborough, Maynard, Medfield, Medway, Millis, Natick, Needham, Newton, Norfolk, Norwood, Plainville, Sharon, Sherborn, Southborough, Stow, Sudbury, Walpole, Waltham, Wayland, Wellesley, Weston, Westwood, Wrentham

  • MassHire Metro North Career Center in Cambridge

    Cambridge · Comprehensive · 617-661-7867

    Mon - Fri 8:30am-4:30pm

Middlesex County economy

  • 3.8%

    unemployment, Sep 2026

    4.1% the month before

  • 932,913

    in the labor force

    Source: BLS Local Area Unemployment Statistics

  • 1,622,896

    people in Middlesex County

    Source: U.S. Census Bureau

  • $126,779

    median household income

    Source: Census ACS

  • 61%

    of workers in white-collar occupations

    Management, business, financial and professional; Census ACS

More cities in Middlesex County

All of Massachusetts

Laid off or looking for work in Cambridge?

See what to do first and the jobs open near you.

See your options after a layoff

Sources: Layoff notices from Massachusetts’s published record; job counts from our live job board, taken from employers’ own career sites; IPEDS for colleges; CareerOneStop for workforce boards and job centers; Census Bureau and BLS for county figures. Massachusetts unemployment benefits and severance rules.

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