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San Diego, CA jobs, layoffs and employers

2,930 open professional jobs in San Diego. Employers filed 14 layoff notices here in the last 12 months. San Diego is in San Diego County.

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Jobs in San Diego

Search all jobs in San Diego

Employers hiring most in San Diego

  1. Qualcomm Inc/De313 open roles
  2. General Atomics101 open roles
  3. Northrop Grumman85 open roles
  4. Qualcomm Technologies77 open roles
  5. Shield AI77 open roles
  6. Intuit75 open roles
  7. UC San Diego65 open roles
  8. Amazon55 open roles
  9. Apple42 open roles
  10. Axos Bank32 open roles

Largest employers headquartered in San Diego

Employee counts with a year are published figures (Wikidata). Other sizes are estimates from our company directory, not payroll counts.

San Diego layoffs

  • 14

    Layoff notices, last 12 months

  • 545

    workers named

    A floor: states may leave out counts

  • 9

    employers

Layoff notices filed in San Diego, newest first
Notice dateEmployerCity or countyWorkersTypeSource
Crinetics PharmaceuticalsTakes effect Jan 4, 2026San Diego County78Layoff PermanentState record
Worldwide Flight ServicesTakes effect Jan 4, 2027San Diego County59Layoff PermanentState record
Avidity Biosciences, Inc.Takes effect Dec 31, 2026San Diego County40Layoff PermanentState record
Becton, Dickinson and Company (BD)Takes effect Sep 1, 2026San Diego County85Layoff PermanentState record
KaiserTakes effect Nov 20, 2026San Diego County72Layoff PermanentState record
KaiserTakes effect Nov 20, 2026San Diego County2Layoff PermanentState record
KaiserTakes effect Nov 20, 2026San Diego County1Layoff PermanentState record
SonTekTakes effect Nov 6, 2026San Diego County36Closure PermanentState record
Blue Shield of CaliforniaTakes effect Oct 20, 2026San Diego County4Layoff PermanentState record
Sharp Metropolitan Medical Campus - Sharp Mesa VistaTakes effect Oct 10, 2026San Diego County134Layoff PermanentState record
Sharp Metropolitan Medical Campus - Sharp Memorial HospitalTakes effect Oct 10, 2026San Diego County20Layoff PermanentState record
Sharp Metropolitan Medical Campus - Sharp Mary Birch HospitalTakes effect Oct 10, 2026San Diego County7Layoff PermanentState record
Sharp Metropolitan Medical Campus - Sharp Outpatient PavilionTakes effect Oct 10, 2026San Diego County5Layoff PermanentState record
Sharp Metropolitan Medical Group - Sharp McDonald CenterTakes effect Oct 10, 2026San Diego County2Layoff PermanentState record

All layoff notices in the state

Colleges in San Diego

Colleges in San Diego
CollegeTypeStudents
National UniversityPrivate non-profit 4-year20,000+
San Diego State UniversityPublic 4-year20,000+
Northcentral UniversityPrivate non-profit 4-year5,000–9,999
University of San DiegoPrivate non-profit 4-year5,000–9,999
Point Loma Nazarene UniversityPrivate non-profit 4-year1,000–4,999
California Western School of LawPrivate non-profit 4-yearUnder 1,000
Franciscan School of TheologyPrivate non-profit 4-yearUnder 1,000
High Tech High Graduate School of EducationPrivate non-profit 4-yearUnder 1,000
The Chicago School at San DiegoPrivate non-profit 4-yearUnder 1,000
Thomas Jefferson School of LawPrivate non-profit 4-yearUnder 1,000

Job fairs and business events in San Diego

Hiring events, career workshops and business events in San Diego.

Conferences in San Diego

Industry conferences and trade shows held in San Diego. 72 with dates announced.

Showing 12 of 92 conferences, 72 with dates announced.

All conferences

Where San Diego ranks

Where San Diego placed in our monthly rankings, month by month. Each month stays online at its own address.

November 2026

San Diego County outlook: Steady

Built from public Bureau of Labor Statistics and Census figures. It describes the area, not any one employer in it.

  • Private-sector jobs up 0.9% from 2022 to 2025
  • Population down 0.6% from 2020 to 2025
  • Unemployment 4.7%, down 0.2 points from a year ago
  • Sectors adding the most jobs: health care (+37,066 jobs), hotels & food (+6,464 jobs)
  • Sectors losing the most jobs: admin & staffing (−9,391 jobs), professional & technical (−8,649 jobs)

Local job-market news

Recent headlines about layoffs, AI and jobs in San Diego. Each link goes to the publisher.

Learn and get funded in San Diego

Workforce development and job centers

The public workforce board and American Job Centers serving San Diego. They offer free help with job search, training and filing for benefits.

Laid off in California? How to file for unemployment in California (steps, weekly amount and the appeal deadline).

  • Metro Career Center

    San Diego · Affiliate

    Monday - Friday 8 a.m. - 5 p.m.

San Diego County economy

  • 4.7%

    unemployment, Sep 2026

    4.9% the month before

  • 1,656,661

    in the labor force

    Source: BLS Local Area Unemployment Statistics

  • 3,282,782

    people in San Diego County

    Source: U.S. Census Bureau

  • $102,285

    median household income

    Source: Census ACS

  • 47%

    of workers in white-collar occupations

    Management, business, financial and professional; Census ACS

More cities in San Diego County

All of California

Laid off or looking for work in San Diego?

See what to do first and the jobs open near you.

See your options after a layoff

Sources: Layoff notices from California’s published record; job counts from our live job board, taken from employers’ own career sites; IPEDS for colleges; CareerOneStop for workforce boards and job centers; Census Bureau and BLS for county figures. California unemployment benefits and severance rules.

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