Software Engineer I/II - Scientific Computing
Iambic Therapeutics
Boston, MA · $129k–$162k a year · Posted September 25, 2026
Just laid off? Start here: a plan for the first weeks
See every open role at Iambic Therapeutics
More in Massachusetts job market · All Software Engineer I jobs (62) · Pharmaceuticals & Biotech · Engineering jobs
More roles at Iambic Therapeutics
- Senior Associate Scientist I/II, Purification Sciences · San Diego, CA
- Research Scientist II/Senior, Discovery Machine Learning · San Diego, CA
- Director, Compensation, Benefits and HR Systems · San Diego, CA
- IT Support Specialist · San Diego, CA
- Research Scientist II/Senior, Computational Chemistry · San Diego, CA
- Sr. Associate Scientist I / II – High Throughput Chemistry · San Diego, CA
Similar jobs
- Vice President - Forward Deployed Engineer · Ameriprise Certificate · Boston, MA
- Senior Manager / Senior Software Engineer – Distribution Analytics, Data Products & AI · Ameriprise Certificate · Boston, MA
- Lead Embedded Software Engineer · Curtiss Wright · MA
- Senior Firmware Engineer · Novanta · Bedford, MA
- Principal Applications Design Engineer · Vicor · Andover, MA
- Product Application Engineer - Semiconductor Fuses and DC Protection · Mersen USA GS · Newburyport, MA
Where Boston, MA ranks
Where Boston, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
How AI is used in this kind of work
Among software developers, AI is already used for some of the tasks. Measured exposure for software developers: 29% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
Say which you have and which you want to build. We use it to match you to jobs like this one.
About the job
JOB SUMMARY
Iambic is seeking a Software Engineer to build software that helps computational chemists run, monitor, and analyze scientific workloads. You will join the Software Engineering group and work closely with computational chemists and machine learning researchers to turn research needs into reliable Python applications and cloud workflows. The role spans design, implementation, deployment, and support for software used in computational drug discovery. This full-time role is based on the US East Coast, ideally in Boston; remote work elsewhere in the United States is also considered.
KEY RESPONSIBILITIES
- Partner closely with computational chemists and machine learning researchers to understand research needs and deliver practical software solutions.
- Build and maintain Python applications, libraries, APIs, and command-line tools.
- Develop reliable workflows for drug discovery workloads.
- Improve orchestration, monitoring, and recovery for workloads on AWS and neo-clouds such as Modal and Lambda.
- Integrate scientific applications with shared data, compute, and model services.
- Troubleshoot issues, document tools, and help scientists use them effectively.
- Contribute to design, testing, review, deployment, and production support.
QUALIFICATIONS
- Bachelor's degree in a relevant technical field and five or more years of software development experience, or equivalent practical experience.
- Strong Python skills and experience writing clear, tested, maintainable production code.
- Experience running scientific or batch workloads on AWS.
- Experience with Prefect or another workflow orchestration system.
- Familiarity with computational chemistry workloads such as molecular dynamics or docking.
- Familiarity with the machine learning model lifecycle
- Strong service mindset, clear communication, and a genuine interest in helping scientists be effective.
ABOUT IAMBIC THERAPEUTICS Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at iambic.ai http://iambic.ai.
MISSION & VALUES Our mission is to make better technology for better medicines. Three values guide how we work:
- Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity.
- Innovative. We are creative and find new solutions that deliver impact.
- Collaborative. We respect one another and partner with integrity.
We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow.
PAY AND BENEFITS The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play.
EQUAL OPPORTUNITY Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.