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Executive Medical Director

Brio

San Diego, CA · Posted October 10, 2026

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About the job

BACK TO JOBS Executive Medical Director APPLY NOW Job Title: Executive Medical Director – Oncology Immunotherapy Company: Biopharma Location: San Diego, CA Brio Resource Group is a Life Sciences Executive Search Firm committed to providing rare talent on an exclusive search basis to the Biopharma, Pharma, Device, and CRO industries. We work on behalf of organizations that value true talent acquisition partners and specialize in supporting emerging Biopharma companies offering life-changing therapies. Our many years of experience, subject matter expertise, comprehensive search process, and genuine passion to deliver rare talent defines Brio. Position Overview: Our client, a clinical-stage biopharmaceutical company developing next-generation immunotherapies for cancer, is seeking an experienced Executive Medical Director to lead the clinical strategy and execution of early-phase oncology trials. The ideal candidate will serve as a senior medical leader across one or more programs in solid tumors or hematologic malignancies, contributing to the advancement of novel therapies in the immuno-oncology space. Opportunity Highlights: Act as clinical lead and source of medical expertise for ongoing and emerging oncology programs Oversee clinical trial design, protocol development, and medical monitoring responsibilities Collaborate cross-functionally with Preclinical, Regulatory, Clinical Operations, and Quality teams to drive clinical program strategy Lead interpretation and presentation of clinical trial data to both internal stakeholders and external experts Develop and review clinical development plans, study reports, investigator brochures, INDs, and regulatory documents Serve as a primary medical liaison to KOLs, investigators, and CROs throughout the course of the trial Provide medical input and support during site training, clinical implementation, and regulatory interactions Position Requirements: MD or DO required, with board certification/eligibility in Oncology highly preferred Clinical experience in prostate or genitourinary cancers is strongly desired 5+ years of industry or academic experience in Oncology clinical development Demonstrated leadership in early-phase clinical trial execution, from concept to IND and beyond Strong grasp of GCP/ICH guidelines and regulatory requirements for oncology trials Excellent interpersonal and communication skills; ability to engage effectively with cross-functional teams, investigators, and senior leadership We welcome the opportunity to provide a full job description upon resume review.