Fractional Chief Financial Officer

BACK TO JOBS Fractional Chief Financial Officer APPLY NOW Fractional Chief Financial Officer Company: Clinical-Stage Biotechnology Company Location: San Francisco, CA Engagement: Fractional Consulting Role The Opportunity Brio Resource Group is partnering with a clinical-stage biotechnology company to identify an experienced Fractional Chief Financial Officer . This executive consulting engagement will provide strategic financial leadership as the company advances its clinical portfolio and prepares for future growth. The ideal candidate combines biotechnology finance expertise with the ability to operate hands-on within a lean organization, advising executive leadership and the Board while strengthening financial planning, controls, reporting, and capital strategy. Key Responsibilities Serve as a strategic financial advisor to the CEO, executive leadership team, and Board of Directors. Lead financial planning, budgeting, forecasting, cash management, and long-range financial modeling. Develop financing strategies aligned with clinical, regulatory, and corporate milestones. Support capital-raising activities, investor engagement, strategic partnerships, and business-development transactions. Provide financial oversight of clinical development programs, vendor commitments, headcount plans, and operating expenses. Strengthen financial reporting, internal controls, accounting processes, and governance. Partner with external accounting, audit, tax, legal, banking, and insurance providers. Prepare financial updates, forecasts, and decision-support materials for leadership and Board meetings. Evaluate licensing, collaboration, acquisition, and other strategic opportunities. Assess organizational needs and help establish a scalable finance infrastructure for continued growth. Qualifications Significant financial leadership experience within biotechnology, pharmaceuticals, or another life sciences organization. Previous CFO, Fractional CFO, or senior finance leadership experience in a clinical-stage biotechnology environment. Demonstrated experience with private and/or public-company financing, investor relations, and Board engagement. Strong understanding of biotechnology development timelines, clinical-program budgeting, cash runway management, and milestone-based planning. Experience supporting fundraising, licensing transactions, strategic partnerships, and financial diligence. Knowledge of GAAP, financial reporting, audit oversight, tax planning, internal controls, and corporate governance. Ability to translate complex financial information into practical strategic guidance. Comfortable operating both strategically and hands-on within a lean, fast-moving organization. CPA, MBA, or other relevant advanced qualification is preferred. Why Consider This Opportunity? This engagement offers the opportunity to work closely with an experienced leadership team, shape financial strategy at a pivotal stage of development, and build the financial foundation required to advance an innovative clinical portfolio and support the company’s next phase of growth.