IT Manager/Sr. IT Manager (Contract-to-Hire)
Frontier Medicines
Boston, MA · Posted November 12, 2026
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November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
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About the job
What’s in it for you?
Frontier Medicines is seeking an IT Manager/Sr. IT Manager to lead our core infrastructure, security, and platform administration as part of a small IT team. You will work hands-on with the systems our scientists and business teams rely on every day, from the data center and network to identity, cloud, and device management.
This is a 3-month contract-to-hire role, with the opportunity to convert to a full-time position if it is a strong fit on both sides. It is an individual contributor role with no direct reports. You will lead your areas from day-to-day administration through planning and vendor relationships, working closely with the rest of the IT team. The ideal candidate is comfortable in a lean, fast-moving biotech environment, works independently, and is ready to take on whatever the environment needs. This role is on site in our Boston office in Seaport.
What will you be doing?
Administer VMware vSphere hosts and virtual machines, patch servers and applications, and monitor capacity and performance
Manage the on-site data center, including server hardware, uptime of the hosting environment, physical access, and the relationship with facility management
Administer TrueNAS and Synology storage systems, and manage Rubrik backups, restore testing, and disaster recovery
Manage Meraki LAN and wireless networks, Palo Alto firewall rules, DNS, and remote access and site-to-site VPNs, and troubleshoot connectivity issues
Administer Okta, including SSO, MFA, access policies, app integrations, and user lifecycle automation
Manage AWS accounts and services by configuring resources, enforcing access controls, and monitoring security posture
Set Intune and Jamf policies, including configuration profiles, compliance rules, security baselines, OS and application updates, and app deployment
Detect and respond to security threats, protect endpoints, email, and the network, and manage vulnerabilities and third-party risk
Traits we believe make a strong candidate:
5+ years of hands-on experience running enterprise IT infrastructure
Expert knowledge of VMware vSphere, enterprise storage, and backup and recovery
Strong understanding of computer architecture, networking, virtualization, storage, and operating systems in a mixed macOS, Windows, and Linux environment, with extensive experience administering and troubleshooting Windows and Linux servers
Experience managing Meraki and Palo Alto networks, including firewall rules and site-to-site VPNs
Experience administering Okta, Intune, and Jamf
Experience managing and securing AWS accounts and services
Ability to troubleshoot complex issues across systems and explain the fix clearly in writing
Ability to work independently on a small team, with sound judgment and excellent attention to detail
Experience in a life sciences or biotech environment strongly preferred
Experience working in a regulated environment, with awareness of compliance standards (e.g., HIPAA, GDPR, Sarbanes-Oxley) and IT control frameworks (e.g., NIST, ISO) preferred
Certifications in VMware, AWS, Okta, or Palo Alto are a plus
Legally authorized to work in the United States
At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $118,000 - $185,000 annually. Compensation for the role will depend on a number of factors, including hours worked, candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.
This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.