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IT Manager/Sr. IT Manager (Contract-to-Hire)

Frontier Medicines

Boston, MA · Posted November 12, 2026

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Skills this job asks for

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  • AWS
  • Lean
  • Linux
  • HIPAA
  • GDPR

About the job

What’s in it for you?

Frontier Medicines is seeking an IT Manager/Sr. IT Manager to lead our core infrastructure, security, and platform administration as part of a small IT team. You will work hands-on with the systems our scientists and business teams rely on every day, from the data center and network to identity, cloud, and device management.

This is a 3-month contract-to-hire role, with the opportunity to convert to a full-time position if it is a strong fit on both sides. It is an individual contributor role with no direct reports. You will lead your areas from day-to-day administration through planning and vendor relationships, working closely with the rest of the IT team. The ideal candidate is comfortable in a lean, fast-moving biotech environment, works independently, and is ready to take on whatever the environment needs. This role is on site in our Boston office in Seaport.

What will you be doing?

Administer VMware vSphere hosts and virtual machines, patch servers and applications, and monitor capacity and performance

Manage the on-site data center, including server hardware, uptime of the hosting environment, physical access, and the relationship with facility management

Administer TrueNAS and Synology storage systems, and manage Rubrik backups, restore testing, and disaster recovery

Manage Meraki LAN and wireless networks, Palo Alto firewall rules, DNS, and remote access and site-to-site VPNs, and troubleshoot connectivity issues

Administer Okta, including SSO, MFA, access policies, app integrations, and user lifecycle automation

Manage AWS accounts and services by configuring resources, enforcing access controls, and monitoring security posture

Set Intune and Jamf policies, including configuration profiles, compliance rules, security baselines, OS and application updates, and app deployment

Detect and respond to security threats, protect endpoints, email, and the network, and manage vulnerabilities and third-party risk

Traits we believe make a strong candidate:

5+ years of hands-on experience running enterprise IT infrastructure

Expert knowledge of VMware vSphere, enterprise storage, and backup and recovery

Strong understanding of computer architecture, networking, virtualization, storage, and operating systems in a mixed macOS, Windows, and Linux environment, with extensive experience administering and troubleshooting Windows and Linux servers

Experience managing Meraki and Palo Alto networks, including firewall rules and site-to-site VPNs

Experience administering Okta, Intune, and Jamf

Experience managing and securing AWS accounts and services

Ability to troubleshoot complex issues across systems and explain the fix clearly in writing

Ability to work independently on a small team, with sound judgment and excellent attention to detail

Experience in a life sciences or biotech environment strongly preferred

Experience working in a regulated environment, with awareness of compliance standards (e.g., HIPAA, GDPR, Sarbanes-Oxley) and IT control frameworks (e.g., NIST, ISO) preferred

Certifications in VMware, AWS, Okta, or Palo Alto are a plus

Legally authorized to work in the United States

At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $118,000 - $185,000 annually. Compensation for the role will depend on a number of factors, including hours worked, candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.

This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.