Senior Software Developer (C++)
Black Canyon Consulting
Bethesda, MD · Posted January 28, 2026
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November 2026
- #9Best all-round cities for mid-career professionals in the Mid-Atlantic62 / 100 · of 37
- #12Best all-round cities for AI careers in the Mid-Atlantic61 / 100 · of 37
- #14Cities with the most jobs that need no experience in the Mid-Atlantic1.4% · of 84
- #18Best cities for pay after cost of living in the Mid-Atlantic$137k · of 37
- #19Best cities for software and engineering jobs in the Mid-Atlantic118 openings · of 68
- #19Best all-round cities for remote workers in the Mid-Atlantic50 / 100 · of 37
Rankings about engineering jobs
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- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
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Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
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About the job
Overview
Black Canyon Consulting (BCC) is searching for a Sr. Software Developer in Bioinformatics and Big Data to support our work for the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), an institute of the National Institutes of Health. This opportunity is full time and onsite at the NIH-NCBI in Bethesda, MD and/or remote work.
NCBI, the National Center for Biotechnology Information, the nation’s premier biomedical resource, is seeking a software developer to help deliver biological sequence annotation and data curation infrastructure for the nation’s foremost sequence and biomedical literature repositories. Sites at NCBI, a part of the National Library of Medicine (NLM) at the National Institutes of Health (NIH), see four million daily users searching for gene sequence data, biomedical journal citations, and a wide array of other information that directly impacts biomedical research and public health. NCBI’s annotation pipelines not only serve these diverse expert communities – they actually drive new life sciences discoveries, ranging from medical health (viruses and pandemics, genetic diseases, cancer) to public health (food safety monitoring, antimicrobial resistance, viral outbreaks), to basic research topics in computational biology, bioinformatics and microbial diversity, and many more.
On a technical level, NCBI’s wide range of applications, platforms (e.g. node, Python, Django, C++), and applications and environments (petabyte-level big data, multiple cloud providers) serve more users than the US Postal Service and see more traffic than the IRS at tax time. We embrace FAIR principles (Findable, Accessible, Interoperable, Reusable) and are on the cutting edge of civic tech and cloud computing.
This role calls for more than an expert coder and architect – someone who can work equally effectively with subject-matter experts, user researchers, designers, product managers, scientists, security and DevOps engineers, and more. Work with teams of dedicated, skilled developers, researchers, and product professionals as you build robust, flexible solutions serving dozens of production applications, APIs and services. Join us!
We attract the best people in the business with our competitive benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, and tuition reimbursement. If you enjoy being a part of a high performing, professional service and technology focused organization, please apply today!
Duties & Responsibilities:
Responsible for the development, implementation, testing, and continued maintenance of NCBI bioinformatics software and information retrieval systems
Work with a diverse group of scientists, bioinformaticians and other developers across the center to implement efficient bioinformatics algorithms
Learn new technologies, keep up with internal systems, and share your knowledge with the team
Required qualifications :
5+ years of experience handling large amounts of data or working in a distributed computing environment
Programming experience in a Linux environment
Proficiency in C++
Experience with MS SQL server and relational database design and optimization
Fluency in some scripting languages such as BASH, csh, Perl, or Python
Preferred qualifications:
5+ years of working with genetic and biological data
Proficiency in Python and/or JavaScript and familiarity with their associated ecosystems
Experience with MongoDB or other NoSQL database technology
Experience with Docker or other containerization mechanisms
Experience with CI/CD pipelines, unit testing, integration and regression testing
Experience using GitHub
Experience with Cloud technologies a strong plus
Benefits and Salary
We attract the best people in the business with our competitive benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, and tuition reimbursement.
We offer a competitive salary commensurate with experience and location. The targeted range for this position is $115,000 - $150,000.
If you enjoy being a part of a high performing, professional service and technology focused organization, please apply today!