Manager, Patient Retention

At Kailera, we are bold, authentic and committed to our mission of developing therapies that give people the power to transform their lives and elevate their overall health. Rooted in an entrepreneurial spirit and a team-oriented culture, we are working together to advance Kailera’s mission to advance novel therapies for obesity and related conditions.

We are passionate about creating an inclusive workplace that promotes collaboration, integrity, and excellence. As we expand, we seek the most talented individuals with diverse backgrounds, cultures, perspectives, and experiences to join our team.

What You’ll Do:

As the Manager, Patient Retention, you will serve as the ultimate operational safeguard for our clinical trial data integrity by actively combating participant dropouts and attrition bias. In this high-impact role, you will monitor early warning systems, tracking eCOA alerts, compliance trends, and site performance metrics in real time. You will act as the vital bridge between Kailera Medical, our CRO partners (IQVIA), and regional CRAs to deploy immediate, tactical interventions for at-risk participants. By turning data insights into rapid clinical action, you will directly protect the statistical power of our landmark GLP-1 pipelines.

Required location: Waltham, MA (hub-based, onsite 3-4 days per week)

Responsibilities:

Monitor and analyze eCOA data portals, weekly compliance logs, and IRT alerts daily to identify early warning signs of participant non-compliance or potential withdrawal

Develop and execute proactive, study-wide retention strategies and site-facing communication frameworks to mitigate visit fatigue and protocol discontinuations

Coordinate joint Kailera/CRO site outreach alongside IQVIA operational leads to provide direct, targeted support to struggling or high-risk clinical sites

Maintain and optimize the internal clinical trial retention tracker, giving leadership and Medical Monitors (MM) immediate, real-time visibility into active retention risks and resolution

Design and distribute high-value site tools, patient counseling cheat sheets, and educational resources regarding the non-linear nature of GLP-1 weight loss journeys

Conduct comprehensive analyses on participant withdrawals to uncover root causes, adjust retention strategies, and clean up historical EDC data

Required Qualifications:

3–5 years of progressive clinical research experience within biotech, pharma, or a major CRO (e.g., as a CRA, Lead Study Coordinator, or Clinical Operations Project Manager)

Advanced proficiency working with critical clinical trial technologies, specifically Electronic Data Capture (EDC), IRT, and eCOA dashboard environments

Proven ability to synthesize complex operational metrics and patient data trends into immediate, actionable risk-mitigation workflows

Exceptional interpersonal and relationship-management skills, with a track record of successfully navigating high-stakes conversations with PIs, coordinators, and external vendors

A proven ability to thrive, self-direct, and execute with precision in a fast-paced, fluid, and entrepreneurial startup culture

Strong emotional intelligence and a solutions-oriented mindset to counsel clinical teams through real-world patient logistics and retention challenges

Preferred Qualifications:

Direct operational experience working on Phase 2 or Phase 3 GLP-1, metabolic, or obesity clinical trials

Prior experience managing complex protocol work alongside large-scale tier-1 CROs

Education:

Bachelor’s degree in life science discipline, healthcare administration, or equivalent practical clinical research experience Salary Range $127,000 — $155,000 USD

For Full Time Roles: This range represents the company’s good-faith estimate of the salary at the time of posting. Actual pay may vary based on experience, skills, qualifications, location, and internal equity. We also offer comprehensive health coverage, flexible time off, paid holidays, and a year-end shutdown. Enjoy a monthly wellness stipend, generous 401(k) match, tuition reimbursement, commuter benefits, disability and life insurance, plus annual bonus opportunities and equity grants—because your well-being and future matter to us.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION:

Kailera Therapeutics, Inc. is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race (including traits historically associated with race, such as hair texture and protective hairstyles), color, creed, religion (including religious dress and grooming practices), national origin, ancestry, citizenship status, age (40 and over), sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, reproductive health decisions, domestic victim status, political affiliation, or any other characteristic protected by applicable federal, state, or local laws and ordinances.

E-Verify:

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