Senior Manager, Clinical Business Operations
Relay Therapeutics
Cambridge, MA · Posted August 25, 2026
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About the job
The Opportunity
The Sr. Manager, Clinical Business Operations will be responsible for managing vendor selection, contracts, budgets and performance metrics. This person will develop and leverage relationships with external vendors for strong business results and know how to structure service agreements/contracts to drive accountability, quality and performance. This role is a key partner to the clinical study teams and will partner with senior level stakeholders to ensure vendors are achieving committed goals and service levels in accordance with executed contracts, budgets and timelines.
Your Role:
You will identify, engage and contract with clinical vendors as well manage relationships with key vendor stakeholders.
You will manage the RFP and vendor selection process.
You will oversee the negotiation and execution of contractual agreements and change orders.
You will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution.
You will partner with finance on the monthly accruals.
You will provide support for financial planning and the financial management of clinical studies, including developing more efficient processes to calculate budgets and track expenses.
You will proactively identify opportunities for operational and process improvements and efficiencies.
Your Background:
You should ideally have 10+ years of experience in clinical vendor management and/or clinical financial management. Sponsor experience is strongly preferred.
You have extensive experience with all aspects of vendor oversight or alliance management: vendor selection, RFP process, contract development, and selection to performance management and continuous improvement of the vendor relationships.
You have expertise working with cross-functional teams, such as clinical operations, finance, legal, quality, systems and process, as well as with corresponding vendor functions
You have a strong understanding of clinical development phase activity finance with hands on financial analytics experience
You have effective negotiation, project management and creative problem-solving skills
You have excellent analytical and quantitative skills
You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment.
You are a creative problem-solver with excellent communication and public speaking skills.
You have strong interpersonal and organizational skills, with a high degree of attention to detail.
You are pragmatic and able to manage multiple projects and needs effectively.
Estimated Salary Range : [ $124,000-$177,000 ]
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
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About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!