Executive Director, Commercial Strategy & Execution
Tango Therapeutics
Boston, MA · $271k–$407k a year · Posted November 8, 2026
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About the job
Company Overview
Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.
Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.
This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.
The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.
Summary
The Executive Director, Commercial Strategy & Execution will lead strategic portfolio or country-level initiatives, drive launch readiness preparation for key markets, help develop and implement strategic and executional plans, optimize sales and marketing operations, and build / adopt commercial capabilities within key markets.
Your Role:
Lead and manage key portfolio or country-level initiatives for the CCO in collaboration with key Commercial functions related to key business priorities
Partner closely with cross-functional groups (e.g., Insights & Analytics, R&D, Market Access, Marketing / Sales, Regulatory Affairs, Finance, and Medical Affairs) for the development and implementation of strategic and executional plans
Continually monitor and analyze market, customer, and competitor trends, incorporating insights into commercial plans
Build launch excellence capabilities to ensure successful, coordinated and cross-functional launch preparations
Drive development of launch plans and tracking tools to advance portfolio commercialization efforts
Partner closely with all cross-functional groups and stakeholders across the company that are involved in Launch Readiness (e.g., Commercial teams, Supply Chain, Manufacturing, Finance, Regulatory Affairs, HR to drive launch preparation and ensure effective communication across the internal teams
Support Alliance Management team with leading and optimizing strategic collaborations by providing appropriate Commercial perspectives and direction to maximize value of global partnerships
Oversee critical initiatives to drive excellence in culture, operations and ways of working
What You Bring:
Bachelor's degree required
Life sciences, biotech, or pharma company professional with 15+ years of experience or equivalent work experience
Prior working experience within a pharma Commercial team and within Oncology
Strong working knowledge of legal landscape, FDA promotional regulations, standard operating procedures, and biotech development process required.
Excellent organizational, analytical, and communication skills
Ability to manage projects and changing priorities, multitask, and meet aggressive deadlines in a fast-paced environment.
Resourceful and driven, enthusiastic to collaborate with cross-functional teams and departments.
Ability to thrive in a dynamic and evolving environment, with a proactive and adaptable mindset to navigate change and drive continuous improvement
#LI-Hybrid
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Salary range $271,200 — $406,800 USD