Executive Director, Biostatistics
Vertex Pharmaceuticals
Boston, MA · $272k–$407k a year · Posted November 5, 2026
Just laid off? Start here: a plan for the first weeks
Want recruiters in Executive Leadership to be able to find you?
Roles at this level, like this one at Vertex Pharmaceuticals, are often filled through recruiters.
See every open role at Vertex Pharmaceuticals
More in Massachusetts job market · Pharmaceuticals & Biotech · Executive Leadership jobs
More roles at Vertex Pharmaceuticals
- Senior Director, Global HEOR, Hemoglobinopathies · Boston, MA
- Senior Director, Immunology · Boston, MA
- Executive Medical Director, Global Medical (Nephrology) · Boston, MA
- Senior Director, Kidney and Patient Support Technology · Boston, MA
- Senior Director, DMPK · San Diego, CA
- Senior Director - US Medical Affairs - Nephrology · Boston, MA
Similar jobs
- Senior Director, Biostatistics · Alkermes plc. · Waltham, MA
- Associate Director, Biostatistics · Alkermes plc. · Waltham, MA
- Sr. Manager or Associate Director or Director, Biostatistics · Kymera Therapeutics · Watertown, MA
- Applied Physical Scientist · Frontier Technology · Beverly, MA
- Senior Applied Physical Scientist · Frontier Technology · Beverly, MA
- Director, Biostatistics · Alnylam Pharmaceuticals · Cambridge, MA
Where Boston, MA ranks
Where Boston, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
How AI is used in this kind of work
Among statisticians, AI is already used for some of the tasks. Measured exposure for statisticians: 21% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
Say which you have and which you want to build. We use it to match you to jobs like this one.
About the job
Job Description
General Summary:
The Executive Director of Biostatistics is a strategic, dynamic, and empowered leader, overseeing statistical functions in support of multiple company therapeutic areas or portfolios. In addition, The incumbent is responsible for the methodological and quantitative scientific contributions of their group while simultaneously driving operational excellence. The Executive Director will have a highly visible and collaborative role, partnering across various R&D functions to generate evidence in support of Vertex pipelines/products.
Key Duties and Responsibilities:
• Is responsible for leading/driving scientific statistical methodological expertise to impact the Vertex portfolio by application of both best in class and novel statistical approaches as part of unified Development strategies. This includes oversight of quantitative methods deployed across the portfolio with an eye towards efficiency and innovation.
• Serve as subject matter expert and owner when appropriate for key biometrics processes and associated operating model(s) related to Biostatistics SOPs, process maps, training and software/tools
• Own statistical support in the therapeutic areas and/or Global Medical Affairs he/she leads including early/late clinical developments, post-marketing studies, RWE studies and/or analyses supporting reimbursement
• Drive innovative trial designs in complex/fast changing environment to improve trial efficiency and shape the views of the executive team on important matters
• Serve as a key Leader on the Biostatistics Leadership Team to help set and drive vision and execution with respect to data operations, statistics, and statistical reporting/analytics.
• Represent Vertex externally, demonstrating scientific leadership and collaborating in industry, academic and regulatory forums as appropriate.
Knowledge and Skills:
• Outstanding communication including clarity in writing including excellence in scientific/technical/process writing, influential speech and negotiation, ability to explain complex concepts to others, willingness and ability to engage in scientific discourse at the executive level.
• Demonstrated experience developing and leading high performing teams.
• Expert in statistical methodology including best practices and new industry trends. Agile learner and change agent.
• Executive presence and high degree of emotional intelligence
Education and Experience:
• An M.S or Ph.D. in Statistics or Biostatistics
• 15 years of relevant work experience or the equivalent combination of education and experience
#LI-JM1
#LI-Hybrid
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range: $271,600 - $407,400
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation: Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid : work remotely up to two days per week; or select 2. On-Site : work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com