Sr. (Lead) Mechanical Engineer - Life Science
Top Echelon Network (recruiter member boards)
Boston, MA · Posted September 28, 2026
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Where Boston, MA ranks
Where Boston, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
How AI is used in this kind of work
AI use among mechanical engineers is little observed so far. Measured exposure for mechanical engineers: 8% (little observed).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
About our client
Our client is an architecture, engineering, and construction management firm focused on pharmaceutical and biotech facilities. Their work includes process and MEP engineering, process architecture, lab planning, and commissioning and qualification. They are adding a senior mechanical engineer to lead the mechanical group in their Boston-area office.
The role
The Lead Mechanical Engineer is responsible for mechanical design on the office's pharmaceutical and biotech projects and for a team of about ten. Projects range from renovations and expansions to new construction, including biologics and cell therapy facilities, aseptic processing, and central utility plants.
The position is based in the Boston area.
What you would be doing
Designing HVAC and process support systems for cGMP spaces, including cleanrooms and aseptic processing areas
Designing central utility systems such as chiller plants
Performing load calculations and equipment selection, and writing specifications
Serving as engineer of record and reviewing the mechanical team's work
Mentoring and developing the engineers in the group
Working directly with clients and supporting proposals and business development
Coordinating with the firm's process, electrical, architecture, and commissioning teams
Supporting construction administration, including submittals, RFIs, and site visits
What we are looking for
Professional Engineer license
Bachelor's degree in mechanical engineering
Significant mechanical design experience on pharmaceutical or biotech facilities, with hands-on cGMP work
Working knowledge of cGMP HVAC requirements, including cleanroom classification and pressurization
Experience leading and mentoring engineers
Comfortable working directly with clients
Familiarity with ISPE Baseline Guides is a plus