Senior Director, Financial Planning & Analysis
Keros Therapeutics
Listing collected from Keros Therapeutics's career site. NextChapter is independent of Keros Therapeutics.
Lexington, MA · $200k–$250k an hour · Posted September 18, 2026
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About the job
At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.
Job Summary
The Senior Director of Financial Planning & Analysis will report to the interim Principal Financial Officer and lead Keros’ financial planning and analysis function. The candidate will be a trusted business advisor to leadership and a proactive partner to the business to ensure that our operational goals are tightly aligned with our financial plans. Furthermore, the candidate will track and manage our financial trajectory and proactively recommend actions to continuously improve financial performance.
Primary Responsibilities
Financial Planning & Analysis
Partner with financial and program leadership to compile and analyze financial plans and ensure those plans are linked to our underlying functional, program, and corporate goals
Lead Keros’ annual budgeting and quarterly forecasting processes
Lead monthly budget-to-actual variances and trending analysis
Prepare management commentary on operational results comparing budgets, forecasts, and actual spend
Proactively recommend actions to ensure actual spend continues to align with financial targets
Prepare regular summaries of financial results to functional and program management
Educate client groups on all aspects of financial policies to ensure full compliance
Ensure functional and program visibility and ownership of Keros’ financial plans
Lead the selection and implementation of a corporate planning tool that would be complement to Keros’ ERP system
Strategic Planning & Analysis
Develop Keros’ long range financial plan by working with leadership to define future operational and translate those plans into financial projections
Maintain Keros’ “corporate model” to quantify various investments scenarios to proactively compute our cash runway, identify value inflections points and opportunities to gate spend, and assess future financing needs. Present findings to senior management
Represent Finance on multiple program teams. Provide visibility to each program’s financial plan, performance versus that plan, as well as levers to ensure financial targets are met. Provide ad-hoc financial and/or business case analyses, as needed
Assist in the development of Key Performance Indicators to be monitored by management
Provide financial support to business development activities particularly with respect to financial modeling, term sheet negotiation, and contracting
Partner with the CFO by supporting ad-hoc initiatives such as assessing pipeline valuation and future value creation
Assist in preparing clear and concise presentations for the Executive Committee and the Board of Directors
Core Competencies (Required Skills)
Collaborative work style in a hands-on, team-oriented environment
Strategic thinker who can champion change and effectively manage all aspects of our financial planning activities
Ability to navigate between strategic thinking and tactical execution
High level of comfort working with and influencing all levels within the organization
Excellent interpersonal and communication skills
A high degree of personal initiative
Superior organizational, planning, and project management skills
Strong ERP system and Excel skills
Detail-oriented, organized, and effective written and verbal communication required
Preferred Skills
7-10+ years of progressive finance experience in a biopharmaceutical or biotechnology organization
Strong background in clinical-stage biotechnology, featuring deep technical familiarity with CRO/CMO contract structures, complex clinical accruals and R&D pipeline
Strong analytical skills with demonstrated business impact in previous leadership roles
Expertise using Excel and PowerPoint
Familiarity with financial planning systems selection and implementation
Education Requirements
Bachelor’s degree in Finance or Accounting required
MBA required
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.
Potential base pay range $200,000 — $250,000 USD
Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Recruitment & Staffing Agencies: Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.