Director Clinical Operations
Aura BioSearch
Boston, MA · Posted October 15, 2026
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Where Boston, MA ranks
Where Boston, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
Rankings about operations jobs
- Best cities for operations jobs #1 New York (1,429 openings)
- Best cities for operations pay after cost of living #1 Reston ($177k)
- Most requested AI skills in operations jobs #1 AI tools in daily work (2.5%)
- AI tools named most often in operations jobs #1 Claude (0.28%)
- Employers with the most operations jobs #1 Amazon (1,480 roles)
How AI is used in this kind of work
Among general and operations managers, AI is already used for some of the tasks. Measured exposure for general and operations managers: 14% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
Director, Clinical Operations Boston
We are working on behalf of our client to find a Director of Clinical Operations based in Boston. This leadership role involves managing oncology trials, overseeing day-to-day operations, and working closely with both internal teams and external partners in a fast-paced environment.
Key Responsibilities:
Oversee clinical trial timelines, risks, and challenges, ensuring accurate and timely delivery
Lead cross-functional collaboration to support clinical trial objectives
Manage trials from start-up through close-out, ensuring all deliverables are on time and within budget
Supervise external partners (CROs) and vendors, addressing issues as they arise
Handle contracts, budgets, and trial agreements, ensuring operational excellence
Mentor and support junior staff as they grow
Requirements:
BA/BS in nursing, biology, or related field (advanced degree preferred)
12+ years in clinical research operations, with at least 2 years in oncology
Early phase experience, including IND submissions
Strong vendor and project management skills
Excellent communication and organizational skills
Knowledge of GCP/ICH guidelines and MS Office proficiency
Ability to work collaboratively with cross-functional teams
This is a pivotal role for a seasoned professional to lead oncology clinical trials in a dynamic and innovative environment.