Member of Technical Staff, Science
LatchBio
San Francisco, CA · Posted November 1, 2026
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Where San Francisco, CA ranks
Where San Francisco, CA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for security jobs316 openings · of 20
- #1Best cities for technology jobs7,178 openings · of 100
- #1Best cities for financial services pay after cost of living$173k · of 33
- #1Best cities for entry-level jobs that want AI skills35% · of 100
- #1Best cities for entry-level jobs that want AI skills in the West Coast35% · of 54
- #1Cities with the most jobs that do not need a four-year degree in the West Coast902 jobs · of 47
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
Pay compared with the market
This listing does not state pay. Across 130 open member of technical staff listings that state pay, the middle half runs $208,000 to $270,000 and the median is $240,000.
Listed pay is what employers advertise, not what people are paid.
Member of Technical Staff salaries by state · Check your own pay
How AI is used in this kind of work
Among software developers, AI is already used for some of the tasks. Measured exposure for software developers: 29% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
About the job
Our mission is to advance humanity's ability to engineer biology. We approach this by understanding and improving AI’s application to biology across basic research, drug discovery, and biosecurity. We are a team of engineers, scientists, and operations specialists who are driven by improving capabilities and interpretability. Some of our work is showcased on benchmarks.bio .
About this role. You’ll turn your understanding of a biological domain into a roadmap of benchmarks and design them with engineers. You’ll then build and manage your own scientific team through your network and internal talent infrastructure.
You have (1) deep scientific expertise and experience using AI tools or (2) rigorous coursework in math/CS with experience working with scientists.
This is a high-intensity, founder-type role. Our Members of Technical Staff have built companies, run drug programs and scaled complex technical projects.
How we work. Our MTS team works in person five days a week in Mission Bay, San Francisco. We keep meetings to a minimum and are flexible about when you arrive or leave. Tight deadlines and customer commitments sometimes require late hours.
Our work in use. Frontier AI labs use our benchmarks to assess biological capabilities and safeguards. Our work appears in research announcements and model cards, including:
Anthropic: Claude Fable 5.1 and Mythos 5.1 system card
Anthropic: Claude Opus 5.5 system card
Anthropic: Advancing Claude in healthcare and life sciences
xAI: Grok 4.7 model card
xAI: Biosecurity at the frontier
Hiring Process.
Our process is typically completed within two weeks.
Round 1: Introduction
Round 2: Technical project matching
Round 3: Take-home evaluation project (~2 hours)
Round 4: Technical interview / live engineering session (1 hour)
Round 5: Paid onsite project and presentation (2–3 days)
Offer
Compensation & Benefits
350K-500K+ OTE
Equity
Unlimited PTO
Health, dental and vision insurance fully covered
Visa sponsorship and relocation assistance
401(k)
Office in Mission Bay, San Francisco
Lunch and dinner provided